Specialty
Kisspeptin-10
Kisspeptin-10 (KP-10, metastin 45-54)
Also known as KP-10 · Metastin 45-54
Kisspeptin-10 is the shortest fully active fragment of kisspeptin, the product of the KISS1 gene. Its discovery reframed reproductive neuroendocrinology: kisspeptin signaling through KISS1R (GPR54) sits upstream of GnRH neurons and is now understood as a gatekeeper of the reproductive axis. Loss-of-function mutations in KISS1R cause hypogonadotropic hypogonadism, which is the genetic evidence anchoring the pathway.
Research applications
- KISS1R (GPR54) receptor binding and activation assays
- GnRH pulse generation studies in hypothalamic models
- Reproductive axis and puberty-onset research
- Metastasis suppression studies (the original KISS1 context)
Storage
Store lyophilized at -20°C protected from light. Reconstituted at 2-8°C for up to 30 days.
Reconstitution
Reconstitute with bacteriostatic water down the vial wall. Swirl gently.
Published literature
410 papers indexed on PubMed for Kisspeptin-10. Showing 6, reviews first.
- 01Roles of the kisspeptin/GPR54 system in pathomechanisms of atherosclerosis
Watanabe T, Sato K · Nutr Metab Cardiovasc Dis · 2020
- 02KISS1 in breast cancer progression and autophagy
Ulasov IV et al. · Cancer Metastasis Rev · 2019
- 03GPR54 and kisspeptin in reproduction
Tena-Sempere M · Hum Reprod Update · 2006
- 04
- 05
- 06
Indexed from PubMed, 2026-07-19. We link to sources rather than reproducing them.
Related compounds
KPV
10mg · COA published
C-terminal tripeptide fragment of α-MSH studied for anti-inflammatory signaling without melanocortin receptor pigmentation effects.
- Purity
- 99.416%
- 3 lab certificates
Thymosin Alpha-1
10mg · COA published
28-amino-acid thymic peptide studied for Toll-like receptor signaling and T-cell maturation.
- Purity
- 99.699%
- 6 lab certificates
PT-141
10mg · COA published
Cyclic heptapeptide melanocortin receptor agonist, a metabolite of melanotan II studied for central MC4R signaling.
- Purity
- 99.022%
- 5 lab certificates
Bacteriostatic Water – for Laboratory Use
10mL, 3mL · Sterile
Reconstitution solution for research: bacteriostatic water, sterile with 0.9% benzyl alcohol. 10mL and 3mL multi-use vials from $9.
- Volume
- 10mL, 3mL
- Grade
- Sterile
The certificate comes first
Every compound’s independent laboratory analysis is published before you buy, not sent on request.
Verify it without us
Each certificate carries a laboratory key. Enter a batch code and check it at the lab directly.
Ships from Orlando, FL
Orders dispatch within 1 business day of cleared payment, with tracking emailed when the parcel is handed to the carrier. Track any order, account or not.
A person answers
Write to [email protected] and a human replies — no ticket bot, no queue number.
How Kisspeptin-10 compares
Side-by-side against the compounds researchers most often weigh it against, with price per milligram, mechanism and the published certificate for each.
Research goals that include Kisspeptin-10
The research areas this compound is grouped under, each with the other compounds studied alongside it and the published certificates for the group.
Kisspeptin-10
From $39