Growth Hormone
Ipamorelin
Ipamorelin (selective GHS-R1a agonist)
Also known as NNC 26-0161
Ipamorelin is a synthetic pentapeptide agonist at the growth hormone secretagogue receptor (GHS-R1a). Its defining research characteristic is selectivity: unlike earlier secretagogues such as GHRP-6 and GHRP-2, it shows minimal effect on ACTH, cortisol, and prolactin at comparable doses in animal models. That clean profile is precisely why it remains a useful tool compound for isolating GH-axis effects.
Research applications
- GHS-R1a receptor selectivity and binding studies
- Pituitary somatotroph response assays
- Comparative secretagogue selectivity profiling
- Pulsatile secretion pattern research
Storage
Store lyophilized powder at -20°C protected from light. Reconstituted solution stable at 2-8°C for up to 30 days.
Reconstitution
Reconstitute with bacteriostatic water directed down the vial wall. Swirl gently.
Published literature
53 papers indexed on PubMed for Ipamorelin. Showing 6, reviews first.
- 01Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions
Rahman OF et al. · J Am Acad Orthop Surg Glob Res Rev · 2026
- 02Injectable Peptide Therapy: A Primer for Orthopaedic and Sports Medicine Physicians
Mayfield CK et al. · Am J Sports Med · 2026
- 03Safety and Efficacy of Approved and Unapproved Peptide Therapies for Musculoskeletal Injuries and Athletic Performance
Mendias CL, Awan TM · Sports Med · 2026
- 04Therapeutic Peptides in Aesthetic, Metabolic and Endocrine Conditions: Effects, Safety, Clinical Applications, and Future Perspectives
Renke G, Chinellato L · Int J Mol Sci · 2026
- 05Therapeutic peptides in gerontology: mechanisms and applications for healthy aging
Mavrych V et al. · Front Aging · 2026
- 06Beyond the androgen receptor: the role of growth hormone secretagogues in the modern management of body composition in hypogonadal males
Sinha DK et al. · Transl Androl Urol · 2020
Indexed from PubMed, 2026-07-19. We link to sources rather than reproducing them.
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How Ipamorelin compares
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Research goals that include Ipamorelin
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Ipamorelin
From $39