Metabolic
Cagrilintide
Cagrilintide (long-acting amylin analog)
Also known as AM833
Cagrilintide is an acylated analog of human amylin, the peptide co-secreted with insulin from pancreatic β-cells. It acts at the calcitonin receptor and amylin receptor subtypes, a pathway entirely separate from GLP-1 and GIP signaling. Research interest centers on whether amylin and incretin pathways are additive, which is why it appears frequently in combination studies alongside semaglutide.
Research applications
- Amylin and calcitonin receptor binding studies
- Combination pharmacology with incretin agonists
- Satiety signaling research in preclinical models
- Gastric emptying rate assays
Storage
Store lyophilized at -20°C protected from light. Reconstituted at 2-8°C for up to 30 days.
Reconstitution
Reconstitute with bacteriostatic water down the vial wall. Swirl gently; do not shake.
Published literature
112 papers indexed on PubMed for Cagrilintide. Showing 6, reviews first.
- 01Novel GLP-1-based Medications for Type 2 Diabetes and Obesity
Son JW et al. · Endocr Rev · 2026
- 02Weight management treatment in obesity
Rubio-Herrera MA, Mera-Carreiro S · Med Clin (Barc) · 2025
- 03Efficacy and Safety of Cagrilintide Alone and in Combination with Semaglutide (Cagrisema) as Anti-Obesity Medications: A Systematic Review and Meta-Analysis
Dutta D et al. · Indian J Endocrinol Metab · 2024
- 04Amylin analogs for the treatment of obesity without diabetes: present and future
Panou T et al. · Expert Rev Clin Pharmacol · 2024
- 05
- 06Coadministered Cagrilintide and Semaglutide in Adults with Overweight or Obesity
Garvey WT et al. · N Engl J Med · 2025
Indexed from PubMed, 2026-07-19. We link to sources rather than reproducing them.
Related compounds
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5–20mg · COA published
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- Purity
- 99.728%
- 9 lab certificates
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Retatrutide
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AOD-9604
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C-terminal fragment of human growth hormone studied for lipolytic activity without the growth-promoting effects of the full hormone.
- Purity
- 99.783%
- 5 lab certificates
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How Cagrilintide compares
Side-by-side against the compounds researchers most often weigh it against, with price per milligram, mechanism and the published certificate for each.
Research goals that include Cagrilintide
The research areas this compound is grouped under, each with the other compounds studied alongside it and the published certificates for the group.
Cagrilintide
From $99